Leptin and obesity

obesity, leptin and leptin receptors

Leptin and Hypertension in Obesity

Leptin, a peptide discovered more than 10 years ago, decreases food intake and increases sympathetic nerve activity to both thermogenic and non-thermogenic tissue. Leptin was initially believed to be an anti-obesity hormone, owing to its metabolic effects. However, obese individuals, for unknown reasons, become resistant to the satiety and weight-reducing effect of the hormone, but preserve lep...

Role of Leptin in Obesity

Obesity has been the problem in the societies of developing and developed world. Some diseases caused by obesity. To overcome of those diseases it is necessary to control obesity. Most of the articles showed that the Leptin may be a vital tool to fight against obesity because it is the anti-obesity hormone. By using leptin therapy may be possible to prevent obesity and diseases like hypertensio...

Leptin, obesity, and obstructive sleep apnea.

T he United States has the notable distinction of having the highest concentration of obese individuals in the world, with a staggering 55% of the adult population being overweight1–3 The body mass index (BMI; weight in kilograms divided by the square of height in meters) is widely used to distinguish between obese and nonobese adults. Overweight is defined as a BMI measure of 25.0 to 29.9 and ...

Obesity, leptin, and incident heart failure.

Obesity has been established as a risk factor for the development of heart failure (HF), independent of the established risk factors for HF such as diabetes and hypertension. Studies have demonstrated a continuous gradient of HF risk with increasing body mass index (BMI) (1,2). Although waist circumference (WC) or waist-hip ratio measurements are more representative of central or abdominal obes...